MANT, TIMOTHY G. K.: search on Z-Library

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1

Pharmacokinetics and Pharmacodynamics of Voxelotor (GBT440) in Healthy Adults and Patients With Sickle Cell Disease

Hutchaleelaha, Athiwat, Patel, Mira, Washington, Carla, Siu, Vincent, Allen, Elizabeth, Oksenberg, Donna, Gretler, Daniel D., Mant, Timothy, Lehrer-Graiwer, Josh

Journal:

British Journal of Clinical Pharmacology

Year:

2019

Language:

english

File:

PDF, 966 KB

english, 2019

2

De novo designed amphipathic α-helical antimicrobial peptides incorporating Dab and Dap residues on the polar face to treat the Gram-negative pathogen, Acinetobacter baumannii.

Mant, Colin T, Jiang, Ziqing, Gera, Lajos, Davis, Timothy, Nelson, Kirsten, Bevers, Shaun, Hodges, Robert S.

Journal:

Journal of Medicinal Chemistry

Year:

2019

Language:

english

File:

PDF, 2.90 MB

english, 2019

3

A phase 1/2 ascending dose study and open-label extension study of voxelotor in patients with sickle cell disease

Howard, Jo, Hemmaway, Claire Jane, Telfer, Paul, Layton, D. Mark, Porter, John, Awogbade, Moji, Mant, Timothy, Gretler, Daniel D., Dufu, Kobina, Hutchaleelaha, Athiwat, Patel, Mira, Siu, Vincent, Dixo

Journal:

Year:

2019

Language:

english

File:

PDF, 284 KB

english, 2019

4

Pharmacokinetics, Tolerability, and Safety of ACP-103 Following Single or Multiple Oral Dose Administration in Healthy Volunteers

Vanover, Kimberly E., Robbins-Weilert, Doris, Wilbraham, Darren G., Mant, Timothy G. K., van Kammen, Daniel P., Davis, Robert E., Weiner, David M.

Journal:

Journal of Clinical Pharmacology

Year:

2007

Language:

english

File:

PDF, 194 KB

english, 2007

5

A phase 1 study of prasugrel in patients with sickle cell disease: pharmacokinetics and effects on ex vivo platelet reactivity

Jakubowski, Joseph A., Zhou, Chunmei, Small, David S., Winters, Kenneth J., Lachno, D. Richard, Frelinger, Andrew L., Howard, Jo, Mant, Timothy G., Jurcevic, Stipo, Payne, Christopher D.

Journal:

British Journal of Clinical Pharmacology

Year:

2013

Language:

english

File:

PDF, 1.11 MB

english, 2013

6

Design of Asynchronous Genetic Circuits

Nguyen, Tramy, Jones, Timothy S., Fontanarrosa, Pedro, Mante, Jeanet V., Zundel, Zach, Densmore, Douglas, Myers, Chris J.

Journal:

Proceedings of the IEEE

Year:

2019

File:

PDF, 55 KB

2019

7

Spatial and socio-demographic determinants of contraceptive use in the Upper East region of Ghana

Achana, Fabian Sebastian, Bawah, Ayaga A, Jackson, Elizabeth F, Welaga, Paul, Awine, Timothy, Asuo-Mante, Eric, Oduro, Abraham, Awoonor-Williams, John Koku, Phillips, James F

Journal:

Reproductive Health

Year:

2015

Language:

english

File:

PDF, 611 KB

english, 2015

8

Mycoplasma pneumoniae and Respiratory Virus Infections in Children With Persistent Cough in England

Wang, Kay, Chalker, Victoria, Bermingham, Alison, Harrison, Timothy, Mant, David, Harnden, Anthony

Journal:

Pediatric Infectious Disease Journal

Year:

2011

Language:

english

File:

PDF, 250 KB

english, 2011

9

Effects of a cytokine inhibitor, JTE-607, on the response to endotoxin in healthy human volunteers

Svetlana Borozdenkova, Timothy G.K. Mant, Elizabeth Allen, Kewei Pu, Shoji Hoshino, Stipo Jurcevic

Journal:

International Immunopharmacology

Year:

2011

Language:

english

File:

PDF, 585 KB

english, 2011

10

Absence of Interaction of Fondaparinux Sodium with Digoxin in Healthy Volunteers

Timothy Mant, Philippe Fournié, Céline Ollier, François Donat…

Journal:

Clinical Pharmacokinetics

Year:

2002

Language:

english

File:

PDF, 130 KB

english, 2002

11

Pharmacokinetics and Safety of CSL112 (Apolipoprotein A-I [Human]) in Adults With Moderate Renal Impairment and Normal Renal Function

Tortorici, Michael A., Duffy, Danielle, Evans, Rebecca, Feaster, John, Gille, Andreas, Mant, Timothy G. K., Wright, Samuel D., D'Andrea, Denise

Journal:

Clinical Pharmacology in Drug Development

Year:

2018

Language:

english

File:

PDF, 473 KB

english, 2018

12

Montelukast for postinfectious cough in adults: a double-blind randomised placebo-controlled trial

Wang, Kay, Birring, Surinder S, Taylor, Kathryn, Fry, Norman K, Hay, Alastair D, Moore, Michael, Jin, Jing, Perera, Rafael, Farmer, Andrew, Little, Paul, Harrison, Timothy G, Mant, David, Harnden, Ant

Journal:

The Lancet Respiratory Medicine

Year:

2014

Language:

english

File:

PDF, 252 KB

english, 2014

13

The effect of prasugrel on ADP-stimulated markers of platelet activation in patients with sickle cell disease

Jakubowski, Joseph A., Zhou, Chunmei, Winters, Kenneth J., Lachno, D. Richard, Howard, Jo, Payne, Christopher D., Mant, Timothy, Jurcevic, Stipo, Frelinger, Andrew L.

Journal:

Year:

2015

Language:

english

File:

PDF, 285 KB

english, 2015

14

Haemodynamic effects of inhibition of nitric oxide synthase and of L-arginine at rest and during exercise

Brett, Sally E., Cockcroft, John R., Mant, Timothy G.K., Ritter, James M., Chowienczyk, Philip J.

Journal:

Journal of Hypertension

Year:

1998

Language:

english

File:

PDF, 304 KB

english, 1998

15

Effect of dexmedetomidine on propofol requirements in healthy subjects

Sandeep Dutta, Michael D. Karol, Theodora Cohen, Ron M. Jones, Timothy Mant

Journal:

Journal of Pharmaceutical Sciences

Year:

2001

Language:

english

File:

PDF, 222 KB

english, 2001

16

Multiple-dose pharmacokinetics of lomefloxacin: Rationale for once-a-day dosing

Timothy G.K. Mant

Journal:

The American Journal of Medicine

Year:

1992

Language:

english

File:

PDF, 753 KB

english, 1992

17

Appoptosin-Mediated Caspase Cleavage of Tau Contributes to Progressive Supranuclear Palsy Pathogenesis

Zhao, Yingjun, Tseng, I-Chu, Heyser, Charles J., Rockenstein, Edward, Mante, Michael, Adame, Anthony, Zheng, Qiuyang, Huang, Timothy, Wang, Xin, Arslan, Pharhad E., Chakrabarty, Paramita, Wu, Chengbia

Journal:

Year:

2015

Language:

english

File:

PDF, 4.01 MB

english, 2015

18

The Effects of Food on the Pharmacokinetics of a Formulated ACP-103 Tablet in Healthy Volunteers

Vanover, Kimberly E., Robbins-Weilert, Doris, Wilbraham, Darren G., Mant, Timothy G. K., van Kammen, Daniel P., Davis, Robert E., Weiner, David M.

Journal:

Journal of Clinical Pharmacology

Year:

2007

Language:

english

File:

PDF, 91 KB

english, 2007

19

Safety and patient response as indicated by biomarker changes to binding immunoglobulin protein in the phase I/IIA RAGULA clinical trial in rheumatoid arthritis

Kirkham, Bruce, Chaabo, Khaldoun, Hall, Christopher, Garrood, Toby, Mant, Timothy, Allen, Elizabeth, Vincent, Alexandra, Vasconcelos, Joana C., Prevost, Andrew T., Panayi, Gabriel S., Corrigall, Valer

Journal:

Year:

2016

Language:

english

File:

PDF, 174 KB

english, 2016

20

A phase II and pharmacokinetic study of enloplatin in patients with platinum refractory advanced ovarian carcinoma

Kudelka, Andrzej P, Siddik, Zahid H, Tresukosol, Damrong, Edwards, Creighton L, Freedman, Ralph S, Madden, Timothy L, Rastogl, Ram, Hord, Mary, Kim, E Edmund, Tornos, Carmen, Mante, Rosario, Kavanagh,

Journal:

Anti-Cancer Drugs

Year:

1997

File:

PDF, 607 KB

1997

21

A phase 1 study of prasugrel in patients with sickle cell disease: Effects on biomarkers of platelet activation and coagulation

Jakubowski, Joseph A., Zhou, Chunmei, Jurcevic, Stipo, Winters, Kenneth J., Lachno, D. Richard, Frelinger, Andrew L., Gupta, Neehar, Howard, Jo, Payne, Christopher D., Mant, Timothy G.

Journal:

Thrombosis Research

Year:

2014

Language:

english

File:

PDF, 555 KB

english, 2014

22

An S-warfarin and AZD1981 interaction: in vitro and clinical pilot data suggest the N-deacetylated amino acid metabolite as the primary perpetrator

Grime, Ken, Pehrson, Rikard, Nordell, Pär, Gillen, Michael, Kühn, Wolfgang, Mant, Timothy, Brännström, Marie, Svanberg, Petter, Jones, Barry, Brealey, Clive

Journal:

British Journal of Clinical Pharmacology

Year:

2017

Language:

english

File:

PDF, 897 KB

english, 2017

23

Safety and Efficacy of RNAi Therapy for Transthyretin Amyloidosis

Coelho, Teresa, Adams, David, Silva, Ana, Lozeron, Pierre, Hawkins, Philip N., Mant, Timothy, Perez, Javier, Chiesa, Joseph, Warrington, Steve, Tranter, Elizabeth, Munisamy, Malathy, Falzone, Rick, Ha

Journal:

New England Journal of Medicine

Year:

2013

Language:

english

File:

PDF, 680 KB

english, 2013

24

De novo designed amphipathic α-helical antimicrobial peptides incorporating Dab and Dap residues on the polar face to treat the Gram-negative pathogen, Acinetobacter baumannii.

Mant, Colin T, Jiang, Ziqing, Gera, Lajos, Davis, Timothy, Nelson, Kirsten, Bevers, Shaun, Hodges, Robert S.

Journal:

Journal of Medicinal Chemistry

Year:

2019

File:

PDF, 2.90 MB

2019

25

Design of Asynchronous Genetic Circuits

Nguyen, Tramy, Jones, Timothy S., Fontanarrosa, Pedro, Mante, Jeanet V., Zundel, Zach, Densmore, Douglas, Myers, Chris J.

Journal:

Proceedings of the IEEE

Year:

2019

Language:

english

File:

PDF, 55 KB

english, 2019

26

Nonlinear multiple-dose pharmacokinetics of the dopamine reuptake inhibitor vanoxerine

Steen H. Ingwersen, Sonja Snel, Timothy G. K. Mant, David Edwards

Journal:

Journal of Pharmaceutical Sciences

Year:

1993

Language:

english

File:

PDF, 386 KB

english, 1993

27

Initial human experience with MK-462 (rizatriptan): a novel 5=HTID agonist

David G. Sciberras, William J. Polvino, Barry J. Gertz, Haiyung Cheng, Michael Stepanavage, Johanna Wittreich, Timothy Olah, Mark Edwards, Timothy Mant

Journal:

British Journal of Clinical Pharmacology

Year:

1997

Language:

english

File:

PDF, 616 KB

english, 1997

28

Pharmacokinetics and safety assessments of high-dose and 4-week treatment with S-3304, a novel matrix metalloproteinase inhibitor, in healthy volunteers

Timothy G. K. Mant, Daniel Bradford, Dipti M. Amin, Jaya Pisupati, Yoshikazu Kambayashi, Yoshitaka Yano, Kazushige Tanaka, Takuko Yamada-Sawada

Journal:

British Journal of Clinical Pharmacology

Year:

2007

Language:

english

File:

PDF, 422 KB

english, 2007

29

Dynamics of acquisition and loss of carriage of Staphylococcus aureus strains in the community: The effect of clonal complex

Miller, Ruth R., Walker, A. Sarah, Godwin, Heather, Fung, Rowena, Votintseva, Antonina, Bowden, Rory, Mant, David, Peto, Timothy E.A., Crook, Derrick W., Knox, Kyle

Journal:

Journal of Infection

Year:

2014

Language:

english

File:

PDF, 1.43 MB

english, 2014

30

Clinical Safety of SonoVue???, a New Contrast Agent for Ultrasound Imaging, in Healthy Volunteers and in Patients with Chronic Obstructive Pulmonary Disease

BOKOR, DANIELA, CHAMBERS, JOHN B., REES, PETER J., MANT, TIMOTHY G. K., LUZZANI, FRANCO, SPINAZZI, ALBERTO

Journal:

Investigative Radiology

Year:

2001

Language:

english

File:

PDF, 41 KB

english, 2001

31

Changes in HLA-DR expression, cytokine production and coagulation following endotoxin infusion in healthy human volunteers

Timothy G.K. Mant, Svetlana Borozdenkova, Daniel B.A. Bradford, Elizabeth Allen, Dipti M. Amin, Roger D. Toothaker, Robert W.M. Collins, Roseanna E.G. Hargreaves, Stipo Jurcevic

Journal:

International Immunopharmacology

Year:

2008

Language:

english

File:

PDF, 587 KB

english, 2008

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